Adapalene

RetinoidAcne Treatment

Also known as: Differin, Third-generation Retinoid

A third-generation synthetic retinoid available OTC (0.1%) and by prescription. More stable and less irritating than tretinoin while maintaining efficacy for acne.

Benefits

Treats acne, prevents new breakouts, mild anti-aging benefits, unclogs pores, reduces inflammation.

How to Use

Apply pea-sized amount to entire face at night on dry skin. Start every other night. Can take 8-12 weeks to see full results.

Technical Details

pH Range5.0-6.0

Typical Concentrations0.1%-0.3%

Research Summary

Well-studied for acne treatment. OTC 0.1% shown effective for mild-moderate acne. Combining with benzoyl peroxide is a gold-standard acne regimen.

What to Avoid With

pregnancy
breastfeeding
eczema (use with caution)

Cautions

Causes dryness and irritation during adaptation period. Increases sun sensitivity. Less irritating than tretinoin but still requires gradual introduction.

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