Skip to main content
← All Ingredients

Glutathione

AntioxidantBrighteningNatural

Also known as: GSH, L-Glutathione, Reduced Glutathione

Best for:AllNormalMatureCombination

A tripeptide antioxidant naturally produced in cells. Known for its skin-brightening properties through inhibition of melanin synthesis.

Routine placement

Serum · AM

Time to results

4-8 weeks for brighter, more even-toned skin

Benefits

Antioxidant, skin brightening, inhibits melanin production, detoxifying, evens skin tone.

How to Use

Apply in serum form. Can be used morning and evening. Works synergistically with Vitamin C.

Technical Details
Typical Concentrations0.5%-2.0%
Research Summary

Key endogenous antioxidant. Oral supplementation shows skin lightening effects. Topical penetration and efficacy still being studied.

Cautions

Topical penetration can be limited. Reduced (active) form is unstable. Effectiveness of topical application debated.

Frequently Asked Questions

What does Glutathione do for skin?

Glutathione is used in skincare primarily as a antioxidant ingredient. Its effects depend on concentration and formulation. Check the benefits section above for specific details.

Is Glutathione safe for sensitive skin?

Glutathione is generally well-tolerated, but sensitivity varies by individual. Start with a patch test if you have reactive skin, and introduce gradually into your routine.

Can I use Glutathione every day?

For most skin types, daily use is appropriate at standard concentrations. If you experience any irritation, reduce frequency to every other day.

How long does Glutathione take to fade dark spots?

Most brightening ingredients take 8-12 weeks of consistent daily use to show visible improvement in hyperpigmentation. Results vary by skin tone and spot severity.

Does your skincare contain Glutathione?

Paste your product's ingredient list to check, or create your Skinularity ID for a full routine.

Find Glutathione products

Browse skincare products containing Glutathione.

Find Products