Cysteamine
BrighteningAntioxidantNaturalAlso known as: Cysteamine HCl, Cysteamine Hydrochloride
A naturally occurring aminothiol with potent depigmenting activity. Works through multiple mechanisms to reduce melanin production.
Potent depigmentation, multiple mechanisms of action, antioxidant, treats melasma and post-inflammatory hyperpigmentation.
Apply at night. Typical protocol: apply, wait 15 minutes, then rinse off. Follow with moisturizer.
Randomized controlled trials show non-inferiority to hydroquinone 4% for melasma with better safety profile. Works via chelating copper and scavenging free radicals.
Cautions
Has an unpleasant sulfur-like odor. Can cause temporary redness and irritation. Rinse-off protocol reduces side effects.
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